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                                          Tεύχος 26 | Nοέμβριος - Δεκέμβριος 2023 Canoxidin®
Prevent Complications Related to Indwelling Urological Medical Devices
    Canoxidin® decreases more than 8 times the probability of severe to complete blockage of urological devices.11
Canoxidin® significantly reduced overall incrustation.11
First in class product
Patent no. WO2015150608 (A1)
L-Methionine Phytin Theobromine
90 tablets
 Canoxidin® allows safer and longer indwelling time of urological devices.
Double J stent Mono J stent
Distributor for Greece:
Intermittent catheterization
Urethral and suprapubic Foley catheters
Nephrostomy and urostomy catheters
Manufactured by:
       T: 21 11 152 356, 6946 72 7001
E: info@medprisma.com, info@lit-control.gr W: www.medprisma.com
1.Vanderbrink BA, Rastinehad AR, Ost MC, Smith AD. Encrusted urinary stents: evaluation and endourologic management. J Endourol. 2008 May;22(5):905-12. doi: 10.1089/end.2006.0382. PMID: 18643720. 2.Nicolle LE. Catheter associated urinary tract infections. Antimicrob Resist Infect Control. 2014;3:23. Published 2014 Jul 25. doi:10.1186/2047-2994-3-23 3.Barros, A. A., et al. Ureteral Stents Technology: Biodegradable and Drug-Eluting Perspective. Reference Module in Materials Science and Materials Engineering Comprehensive Biomaterials II, Volume 7, 2017, Pages 793-812. 4.Türk C, et al. Guidelines on Urolithiasis. European Association of Urology 2016. Update 2018 https://uroweb.org/guideline/urolithiasis/#4 5.Siener R, Struwe F, Hesse A. Effect of L-Methionine on the Risk of Phosphate Stone Formation. Urology. 2016 Dec;98:39-43. 6.Grases F., Ramis, M., Costa-Bauza, A. Effects of phytate and pyrophosphate on brushite and hydroxyapatite crystallization – Comparison with the action of other polyphosphates, Urol. Res. 2000, 28, 136–140. 7.Conte et al, Urinary lithogenic risk test: Usefulness in the evaluation of renal lithiasis treatment using crystallization inhibitors (citrate vs phytate), Arch. Esp. Urol. 52, 3 (305-3/0), 1999. 8.Curhan et al, Dietary factors and the risk of incident Kidney Stones in Younger Women. Arch Intern Med. 2004;164:885-891. 9. Grases F, Rodríguez A, Costa-Bauza A. et al. Theobromine inhibits uric acid crystallization. A potential application in the treatment of uric acid nephrolithiasis. PLoS ONE 9(10): e111184.10.Hernandez Y, et al. Comparison of Two Dietary Supplements for Treatment of Uric Acid Renal Lithiasis: Citrate vs. Citrate + Theobromine. Nutrients 2020. 11.Torrecilla C, et al. Reduction of ureteral stent encrustation by modulating the urine pH and inhibiting the crystal fi lm with a new oral composition: a multicenter, placebo controlled, double blind, randomized clinical trial. BMC Urol. 2020 Jun 5;20(1):65.
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